Endocrine Abstracts

Aim: In this study, our aim was to investigate frequency of impaired glucose tolerance (IGT), undiagnosed diabetes mellitus (DM) and presence of insulin resistance by HOMA.Material and method: Fifty-five primary hyperparathyroid patients without known glucose tolerance were included in this study. The control group was with similar BMI, normocalcemic, without known glucose tolerance. Seventy-five gram oral glucose tolerans test was performed to PHP patie...

Aim: In this study our aim was to evaluate clinical and laboratory findings of our primary hyperparathyroid patients and detect complications caused by hyperparathroidism.Method: Eighty-three patients (73 women, 10 men) were included in this study. Serum calcium (Ca), phosphorus (P), parathormone (PTH), 25(OH) D, 24 hour urine Ca and P levels, bone mineral density (BMD) and renal ultrasonography were evaluated.Results: The mean age...

Objective: Vitamin D deficiency has been shown to alter insulin synthesis and secretion in both humans and animal models. However, less is known on the association between vitamin D and type 2 diabetes mellitus. In the current study we aimed to analyze the relationship between vitamin D levels with glycemic control in type 2 diabetic patients.Material and methods: Three hundred and twenty diabetic patients who are follow up at least 6 months for diabetes...

Objective: The prevalence and incidence of diabetes mellitus (DM) are increasing at all ages, including older populations. Several studies have shown that elderly diabetics have impaired cognitive function compared to age-matched non-diabetics, as well as a higher risk of dementia. In the current study we aimed to analyze relationship between microalbuminuria and cognitive dysfunction in elderly patients with type 2 diabetes.Material and Methods: One hun...

In prolactinomas, today first choice of treatment is medical treatment with dopamine agonists. Cavernous sinus invasion is not uncommon in prolactinomas and stands out as a blocking factor for surgical removal of the tumor fully. In our study, the presence of cavernous sinus invasion was to investigate the effect on the results of surgical and medical treatment in prolactinomas.Eighty-seven patients followed up with a diagnosis of prolactinoma were inclu...

Prolactinomas are more common tumors by 60% among the hypophysis adenomas. These are often benign, but may present differences in terms of tumor size and treatment responses. Aim of this study was investigate the relationship of serum prolactin levels with tumor size and invasiveness in the prolactinomas.113 patients with the diagnosis of prolactinoma were included to study. Pretreatment plasma levels of prolactin in the time of diagnosis and sella MR im...

Aim: In this study, we aimed to evaluate thyroid functions, thyroid antibody positivity, thyroid ultrasonography (US) findings and prevalence of thyroid cancer in patients with colon cancer and benign colon polyps. Also, we aimed to compare prevalence of thyroid diseases in two groups.Materials and methods: Fifty-seven patients with colon cancer and 50 patients with colon polyps were included in the study. All patients were evaluated with thyroid US and ...

Introduction: Diagnosis of autoimmune thyroiditis is made by determination of elevated antibodies against thyroid peroxidase and thyroglobulin, and a hypoechoic pattern in ultrasound. In the present study we have performed a grey-scale quantitative analysis of thyroid echogenicity in the patients affected by autoimmune thyroiditis, obtaining the degree of hypoechogenicity associated with the appearance of thyroid dysfunction.Material and methods: Six hun...

Cycline D1 gene that plays a crucial role in a cell cycle, have been shown to be expressed more in nonfunctioning pituitary adenomas and functioning invasive pituitary adenomas compared to normal hypophisis tissue and noninvasive pituitary adenomas. A/G polymorphism in CyD1 gene exon 4/intron 4 regions have been demonstrated to affect clinical outcomes and survey in some tumors. Objective of this study was to investigate the effect of polymorphism of cycline D1 gene on the tum...

Majority of prolactinomas consists of the small microadenomas that can be treated with dopamine agonists, but they can present different biological behavior features and not infrequently seen as macroadenomas or in giant adenoma size. There are different results on finding of studies which investigate the relationship between high levels of cell proliferation indicators with tumor behavior in pituitary adenomas. In this study, Ki 67 index to investigate the relationship betwee...